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1969 · Klingenberg — Measurement of human uterine cervical blood flow by local hydrogen gas clearance.

Original title: Measurement of human uterine cervical blood flow by local hydrogen gas clearance.

Super-Abstract

This study measured blood flow in the human uterine cervix using local hydrogen gas clearance — an early attempt to quantify perfusion in a gynaecological tissue that is difficult to assess by other means. The technique offered local, quantitative perfusion data in obstetric/gynaecological contexts. (Acta Obstetricia et Gynecologica Scandinavica, 1969.)

Classified as a Pilot / Observational study using . See Methodology for how we grade evidence.

Commentary

This study applies the hydrogen clearance technique — in which locally administered or inhaled H₂ is washed out by blood flow and the clearance curve used to calculate perfusion — to measure blood supply in the uterine cervix. The clinical relevance at the time would have included assessment of cervical vascularisation in conditions such as carcinoma, pregnancy changes, or chronic inflammatory states. H₂ is an inert tracer here, chosen for its physical properties (small molecule, uncharged, crosses membranes rapidly, detectable with platinum electrodes). This is not a study of H₂ therapy. No abstract text was available for this article.

Key quotes

  1. „Measurement of human uterine cervical blood flow by local hydrogen gas clearance.“ — title-level summary — no abstract available; H₂ used as perfusion tracer in gynaecological tissue

Our assessment

This study has no relevance to H₂ therapy. It is an obstetric/gynaecological physiology study using hydrogen gas clearance to measure local blood flow in the uterine cervix. H₂ functions as an inert diagnostic tracer. No abstract was available; assessment based on title, journal, and the hydrogen clearance method. Off-topic for a therapeutic H₂ database.

Study design

Source & links

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Screenshot — PubMed 5378111

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