1969 · Muller — Hydrogen inhalation curves in cardiologic diagnosis of children.
Super-Abstract
This study evaluated hydrogen inhalation curves obtained during cardiac catheterisation in children to detect and localise intracardiac shunts. Inhaled hydrogen gas, detected by a platinum electrode catheter, produced characteristic arrival-time curves that distinguished left-to-right shunts by their haemodynamic signatures. (Nederlands Tijdschrift voor Geneeskunde, 1969.)
Commentary
This paediatric cardiology study uses the hydrogen indicator-dilution technique — a diagnostic method in which small amounts of hydrogen gas are inhaled, cross the pulmonary membrane, and are detected by an intracardiac platinum electrode. The timing and shape of the resulting detection curve reveal the presence, location, and rough magnitude of intracardiac shunts (abnormal connections between heart chambers or great vessels). This technique was used in paediatric patients where radiation exposure from angiography was a concern. H₂ is an inert tracer here, exploiting its diffusibility and ease of electrochemical detection — not a therapeutic agent. No abstract text was available for this article.
Key quotes
- „Hydrogen inhalation curves in cardiologic diagnosis of children.“ — title-level summary — no abstract available; H₂ used as inert diagnostic tracer in paediatric cardiology
Our assessment
This study has no relevance to H₂ therapy. It is a paediatric cardiology diagnostic study employing hydrogen as an inert haemodynamic tracer. The cardiac indication (shunt detection) is the clinical context; H₂ is the tool. No abstract was available; assessment based on title, journal context, and the established hydrogen indicator method. Off-topic for a therapeutic H₂ database.
Study design
- Type: diagnostic methodology study, paediatric cardiology · n: not stated · H₂ delivery: inhaled H₂ as haemodynamic tracer (indicator-dilution/clearance method) — NOT therapeutic
- Indication: detection and localisation of intracardiac shunts in children · Result: characteristic H₂ detection curves used to identify shunt type and location; no abstract available
Source & links
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