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2009 · Mahlen — Oral abscess caused by Campylobacter rectus: case report and literature review.

Original title: Oral abscess caused by Campylobacter rectus: case report and literature review.

Super-Abstract

This case report and literature review describes the first documented case of a palate abscess caused by Campylobacter rectus in a patient with gastroesophageal adenocarcinoma. The organism was cultured under anaerobic conditions without additional hydrogen gas in the atmosphere, which is notable because C. rectus typically requires H₂ or formate as an electron donor to grow. (Journal of Clinical Microbiology, 2009.)

Classified as a Review / Meta-analysis study using Inhalation, Drinking (HRW). See Methodology for how we grade evidence.

Commentary

This is a clinical microbiology case report, not a study of hydrogen therapy. The relevance to molecular H₂ is microbiological: Campylobacter rectus is an anaerobic bacterium that can use hydrogen gas as an energy source for growth. The authors note that the organism was isolated without additional H₂ in the culture atmosphere, suggesting this strain can survive and infect without relying on exogenous H₂. The paper reviews the atmospheric requirements and growth conditions of C. rectus. This work does not address therapeutic use of H₂, H₂-rich water, or hydrogen inhalation in any clinical context. It is primarily relevant to clinical microbiology and infectious disease, not to the H₂ therapy field.

Key quotes

  1. „Campylobacter rectus was isolated under routine anaerobic conditions (no additional hydrogen gas in the atmosphere) from an oral, nonperiodontal abscess from a patient with gastroesophageal adenocarcinoma.“ — the key clinical and microbiological finding — unusual isolation without H₂ atmosphere
  2. „We report the first case of a palate abscess caused by C. rectus and review the literature and atmospheric requirements of this organism.“ — the scope of this case report: first palate abscess case + literature review of C. rectus biology

Our assessment

This paper is a clinical microbiology case report and literature review. Its connection to molecular H₂ is indirect — it concerns a bacterium that can metabolize H₂ as a growth substrate, not H₂ as a therapeutic agent. The study provides no evidence about therapeutic hydrogen use in humans. It is not a source for claims about H₂ health effects. For completeness: the patient had a rare non-periodontal oral abscess with an unusual oral pathogen.

Study design

Abstract

Campylobacter rectus was isolated under routine anaerobic conditions (no additional hydrogen gas in the atmosphere) from an oral, nonperiodontal abscess from a patient with gastroesophageal adenocarcinoma. We report the first case of a palate abscess caused by C. rectus and review the literature and atmospheric requirements of this organism.

Source & links

Screenshot of the PubMed page

Screenshot — PubMed 19109480

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