Oral health
Oral and dental health (for example periodontitis), assessed through inflammation markers.
Human studies on molecular hydrogen for Oral health. This page collects the 9 studies catalogued in this area — 0 randomized trials, 0 pilot/observational studies and 3 reviews. Listed newest first.
2024 · Afkhami — Exploring Approaches to Pulp Vitality Assessment: A Scoping Review of Nontraditional Methods
Accurate assessment of dental pulp vitality is critical in endodontics — yet current clinical tests are imprecise.
2009 · Mahlen — Oral abscess caused by Campylobacter rectus: case report and literature review.
This case report and literature review describes the first documented case of a palate abscess caused by Campylobacter rectus in a patient with gastroesophageal adenocarcinoma.
2024 · Wang — Combined use of hydrogen-rich water and enzyme-digested edible bird's nest improves PMA/LPS-impaired wound healing in human inflammatory gingival tissue equivalents.
In a laboratory model of inflamed human gum tissue, the combination of hydrogen-rich water and a processed form of edible bird's nest significantly counteracted the wound-healing damage caused by an inflammatory stimulus.
2022 · Saitoh — Molecular hydrogen suppresses Porphyromonas gingivalis lipopolysaccharide-induced increases in interleukin-1 alpha and interleukin-6 secretion in human gingival cells.
In a laboratory cell model of periodontitis, molecular hydrogen (H₂) significantly reduced the secretion of two key inflammatory cytokines — IL-1α and IL-6 — triggered by a major periodontal pathogen.
2019 · Amberg — Effect of Physical Cues of Altered Extract Media from Biodegradable Magnesium Implants on Human Gingival Fibroblasts
As biodegradable magnesium (Mg) implants corrode, they alter the surrounding medium with elevated Mg²⁺, reduced Ca²⁺, increased osmolality, and dissolved molecular hydrogen (H₂) — all of which affect the migration rate of human gingival fibroblasts.
2018 · Zhou — Protective effects of hydrogen-rich medium on lipopolysaccharide-induced injury in human periodontal ligament cells
In cultured human periodontal ligament cells (hPDLCs) exposed to lipopolysaccharide (LPS) to simulate bacterial inflammation, hydrogen-rich medium improved cell proliferation, reduced apoptosis, and lowered oxidative stress markers.
2017 · Kim — Inhibition of Streptococcal Biofilm by Hydrogen Water
Electrolyzed hydrogen-rich water significantly inhibited streptococcal biofilm formation in laboratory cultures, reduced the expression of key biofilm-related genes, and — in a small oral-rinse trial — reduced the number of salivary streptococci compared with tap water.
2012 · Baxter et al. — Evaluation of outgassing, tear strength, and detail reproduction in alginate substitute materials.
This study compares dental impression materials (alginate substitutes) to traditional alginate for three performance properties: the release of hydrogen gas (outgassing), tear strength, and detail reproduction quality.