Fundamentals

Foundational work on understanding molecular hydrogen in the body.

Human studies on molecular hydrogen for Fundamentals. This page collects the 19 studies catalogued in this area — 3 randomized trials, 1 pilot/observational studies and 11 reviews. Listed newest first.

2024 · Dhillon — Hydrogen Water: Extra Healthy or a Hoax?—A Systematic Review

2023 · Artamonov — Molecular Hydrogen: From Molecular Effects to Stem Cells Management and Tissue Regeneration

2023 · Kuo — Molecular Hydrogen: Emerging Treatment for Stroke Management

2022 · LeBaron — Electrolyzed-Reduced Water: Review I. Molecular Hydrogen Is the Exclusive Agent Responsible for the Therapeutic Effects

2021 · Qi — Perspective of Molecular Hydrogen in the Treatment of Sepsis

2021 · Noda — Neuroprotective and Preventative Effects of Molecular Hydrogen

2020 · Hu — Molecular hydrogen: A potential radioprotective agent

2020 · Wang — Prospects of molecular hydrogen in perioperative neuroprotection from basic research to clinical application

2019 · Zhou — Micro/Nanomaterials-Augmented Hydrogen Therapy

2017 · Iketani — Molecular Hydrogen as a Neuroprotective Agent

2012 · Chuai — Molecular hydrogen and radiation protection

2026 · Grepl — Sixty-minute inhalation of molecular hydrogen decreases blood oxygen saturation but does not alter autonomic cardiac regulation at rest in healthy females: a randomized, double-blind, placebo-controlled crossover study

2024 · Chair — The impact of hydrogen inhalation therapy on blood reactive oxygen species levels: A randomized controlled study

2020 · Sim — Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults: a randomized, double-blind, controlled trial

2021 · Kato — Heat-retention effects of hydrogen-rich water bath assessed by thermography for humans

2025 · An — Hydrogen activates ACOD1-itaconate pathway to ameliorate steroid-associated osteonecrosis

2024 · Cui — High-concentration hydrogen inhalation mitigates sepsis-associated encephalopathy in mice by improving mitochondrial dynamics

2024 · Wang — Natural hydrogen gas and engineered microalgae prevent acute lung injury in sepsis

2007 · Ohsawa — Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals