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Other topics that do not clearly fit any of the remaining categories.

Human studies on molecular hydrogen for Other. This page collects the 92 studies catalogued in this area — 4 randomized trials, 20 pilot/observational studies and 15 reviews. Listed newest first.

2024 Review / Meta-analysis Inhalation

2024 · Khan — Catalytic innovations: Improving wastewater treatment and hydrogen generation technologies.

Journal of environmental management
2024 Review / Meta-analysis Inhalation

2024 · James et al. — The Synergistic Potential of Hydrogen Inhalation and Hyperbaric Oxygen Therapy

Journal of vascular surgery
2023 Review / Meta-analysis Saline / IV

2023 · Wong — A potential clinical application of hydrogen-rich saline in postoperative care

Journal of pediatric surgery
2015 Review / Meta-analysis Unspecified

2015 · Ohta — Initiation, Development and Potential of Hydrogen Medicine: Toward Therapeutic and Preventive Applications of Molecular Hydrogen Against a Variety of Diseases

Seikagaku. The Journal of Japanese Biochemical Society
2015 Review / Meta-analysis Unspecified

2015 · Vogt et al. — Chemical communication in the gut: Effects of microbiota-generated metabolites on gastrointestinal bacterial pathogens.

Anaerobe
2015 Review / Meta-analysis Inhalation

2015 · Torzillo et al. — Advances in the biotechnology of hydrogen production with the microalga Chlamydomonas reinhardtii.

Critical reviews in biotechnology
2012 Review / Meta-analysis Unspecified

2012 · Tran et al. — Proton reduction to hydrogen in biological and chemical systems.

Physical chemistry chemical physics : PCCP
2010 Review / Meta-analysis Drinking (HRW)

2010 · Woods — Computational glycoscience: characterizing the spatial and temporal properties of glycans and glycan-protein complexes.

Current opinion in structural biology
2006 Review / Meta-analysis Unspecified

2006 · Klemperer — Interstellar chemistry

Proceedings of the National Academy of Sciences of the United States of America
2002 Review / Meta-analysis Unspecified

2002 · Nicolet et al. — Fe-only hydrogenases: structure, function and evolution

Journal of inorganic biochemistry
1999 Review / Meta-analysis Inhalation

1999 · Särnblad — Lactose intolerance in children. An analysis of hydrogen gas in exhaled air simplifies and improves diagnosis.

Lakartidningen
1994 Review / Meta-analysis Inhalation

1994 · Beglinger — Breath Tests: A Clarification of the Topic

Bildgebung = Imaging
1988 Review / Meta-analysis InhalationDrinking (HRW)

1988 · Scrimshaw — The acceptability of milk and milk products in populations with a high prevalence of lactose intolerance.

The American journal of clinical nutrition
1988 Review / Meta-analysis InhalationDrinking (HRW)

1988 · Holm — Role of blood flow in gastric acid secretion.

The American journal of physiology
1983 Review / Meta-analysis Inhalation

1983 · Ostrander — Breath hydrogen analysis: a review of the methodologies and clinical applications.

Journal of pediatric gastroenterology and nutrition
2013 RCT Human H₂ therapy Drinking (HRW)

2013 · Matsumoto et al. — Effect of supplementation with hydrogen-rich water in patients with interstitial cystitis/painful bladder syndrome.

Urology
1998 RCT

1998 · Evans — Fructose-sorbitol malabsorption and symptom provocation in irritable bowel syndrome: relationship to enteric hypersensitivity and dysmotility.

Scandinavian journal of gastroenterology
1996 RCT

1996 · Hertzler et al. — How much lactose is low lactose?

Journal of the American Dietetic Association
1986 RCT

1986 · Beck et al. — Comparison of Oral Lavage Methods for Preoperative Colonic Cleansing

Diseases of the colon and rectum
2023 Pilot / Observational

2023 · Kiyama — Changes in the negative logarithm of end-tidal hydrogen partial pressure indicate the variation of electrode potential in healthy Japanese subjects.

Scientific reports
2021 Pilot / Observational

2021 · Haworth — The prevalence of intestinal dysbiosis in patients referred for antireflux surgery

Surgical endoscopy
2015 Pilot / Observational

2015 · Bae et al. — Determination of rifaximin treatment period according to lactulose breath test values in nonconstipated irritable bowel syndrome subjects.

Journal of Korean medical science
2012 Pilot / Observational Human H₂ therapy Drinking (HRW)

2012 · Ostojic — Serum alkalinization and hydrogen-rich water in healthy men.

Mayo Clinic proceedings
2012 Pilot / Observational Human H₂ therapy Drinking (HRW)

2012 · Shimouchi et al. — Estimation of Molecular Hydrogen Consumption in the Human Whole Body after Ingestion of Hydrogen-Rich Water

Advances in experimental medicine and biology
2008 Pilot / Observational

2008 · Urita et al. — Extensive Atrophic Gastritis Linked to Increased Levels of Intraluminal Hydrogen Gas

Hepato-gastroenterology
2003 Pilot / Observational

2003 · Terai — Detection of flatus using a portable hydrogen gas analyzer.

Journal of clinical anesthesia
2003 Pilot / Observational

2003 · Oku — Comparison of digestibility and breath hydrogen gas excretion of fructo-oligosaccharide, galactosyl-sucrose, and isomalto-oligosaccharide in healthy human subjects.

European journal of clinical nutrition
2001 Pilot / Observational

2001 · Goodman — Lactulose-induced pneumatosis intestinalis and pneumoperitoneum.

Digestive diseases and sciences
1988 Pilot / Observational

1988 · Wytock et al. — All Yogurts Are Not Created Equal

The American journal of clinical nutrition
1985 Pilot / Observational

1985 · Hanson et al. — Dietary Fiber Effects on Passage Rate and Breath Hydrogen

The American journal of clinical nutrition
1984 Pilot / Observational

1984 · Nishiwaki et al. — Endoscopic Measurement of Gastric Mucosal Blood Flow by Hydrogen Gas Generated by Electrolysis — Comparison with H₂ Inhalation Method

Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
1984 Pilot / Observational

1984 · Hiramatsu et al. — Endoscopical Determination of Gastric Mucosal Blood Flow by the Crossed Thermocouple Method

Gastroenterologia Japonica
1984 Pilot / Observational

1984 · Dolmans et al. — The Determination of Hydrogen Gas in Expired Air for the Diagnosis of Carbohydrate Resorption Disorders

Nederlands tijdschrift voor geneeskunde
1972 Pilot / Observational

1972 · Sem-Jacobsen — Measurements in man of focal intracerebral blood flow around depth-electrodes with hydrogen gas.

Progress in brain research
1969 Pilot / Observational

1969 · Levitt — Production and excretion of hydrogen gas in man.

The New England journal of medicine
1969 Pilot / Observational

1969 · Klingenberg — Measurement of human uterine cervical blood flow by local hydrogen gas clearance.

Acta obstetricia et gynecologica Scandinavica
1965 Pilot / Observational

1965 · Heimann — The use of hydrogen inhalation in the detection of intracardiac shunts.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
1965 Pilot / Observational

1965 · Cosyns — Detection of minimal left-right shunts by hydrogen inhalation.

Acta cardiologica
1963 Pilot / Observational

1963 · HUGENHOLTZ — The clinical usefulness of hydrogen gas as an indicator of left-to-right shunts.

Circulation
2025 Mechanism / Preclinical Inhalation

2025 · Du — A partially degradable composite consisting of Ti-Zr-Cu-Pd-Sn metallic glass and Fe-Mg alloy for orthopedic applications.

Acta biomaterialia
2022 Mechanism / Preclinical Unspecified

2022 · González et al. — Dehydrochlorination of PCDDs on SWCN-Supported Ni₁₀ and Ni₁₃ Clusters: A DFT Study

Molecules (Basel, Switzerland)
2022 Mechanism / Preclinical InhalationBath / Topical

2022 · Yamamoto et al. — Development of a Model System for Gas Cavity Formation Behavior of Magnesium Alloy Implantation

ACS biomaterials science & engineering
2022 Mechanism / Preclinical Drinking (HRW)

2022 · Bulut — Hydrogen-rich water can reduce the formation of biogenic amines in butter

Food chemistry
2022 Mechanism / Preclinical Unspecified

2022 · Wang — Regulation of chlorothalonil degradation by molecular hydrogen

Journal of hazardous materials
2021 Mechanism / Preclinical InhalationBath / Topical

2021 · Hartjen — Toward Tailoring the Degradation Rate of Magnesium-Based Biomaterials for Various Medical Applications: Assessing Corrosion, Cytocompatibility and Immunological Effects

International journal of molecular sciences
2021 Mechanism / Preclinical Inhalation

2021 · Duffner — Dechloromonas and close relatives prevail during hydrogenotrophic denitrification in stimulated microcosms with oxic aquifer material

FEMS microbiology ecology
2020 Mechanism / Preclinical Unspecified

2020 · Ichikawa et al. — Proposal of next-generation medical care „Mega-hydrogen Therapy”

Medical gas research
2020 Mechanism / Preclinical Unspecified

2020 · Murugesan et al. — Catalytic reductive aminations using molecular hydrogen for synthesis of different kinds of amines

Chemical Society reviews
2019 Mechanism / Preclinical Unspecified

2019 · Herdendorf — Staphylococcus aureus Evasion Proteins EapH1 and EapH2: Residue-Level Investigation of an Alternative Binding Motif for Human Neutrophil Elastase

Archives of biochemistry and biophysics
2019 Mechanism / Preclinical Inhalation

2019 · Jung — In Vivo Simulation of Magnesium Degradability Using a New Fluid Dynamic Bench Testing Approach

International journal of molecular sciences
2019 Mechanism / Preclinical Unspecified

2019 · Schmidt — Lifetime of Parahydrogen in Aqueous Solutions and Human Blood

Chemphyschem : a European journal of chemical physics and physical chemistry
2019 Mechanism / Preclinical Unspecified

2019 · Moon — Different Molecular Interaction between Collagen and α- or β-Chitin in Mechanically Improved Electrospun Composite

Marine drugs
2018 Mechanism / Preclinical Unspecified

2018 · Karunakaran — A molecular dynamics approach to explore the structural characterisation of cataract causing mutation R58H on human γD crystallin

Molecular and cellular biochemistry
2017 Mechanism / Preclinical Unspecified

2017 · Ben Hassen Trabelsi — Hydrogen-Rich Syngas Production from Gasification and Pyrolysis of Solar Dried Sewage Sludge: Experimental and Modelling Investigations

BioMed research international
2017 Mechanism / Preclinical Inhalation

2017 · Asanuma — Translational Study of Hydrogen Gas Inhalation as Adjuncts to Reperfusion Therapy for Acute Myocardial Infarction

Circulation journal : official journal of the Japanese Circulation Society
2017 Mechanism / Preclinical Unspecified

2017 · Ostojic — Non-Gut Microbiota as a Source of Bioactive Hydrogen

Postgraduate medical journal
2017 Mechanism / Preclinical Drinking (HRW)

2017 · Rigdon — Evaluation of Alkaline Electrolyzed Water to Replace Traditional Phosphate Enhancement Solutions: Effects on Water Holding Capacity, Tenderness, and Sensory Characteristics

Meat science
2016 Mechanism / Preclinical Unspecified

2016 · Lipinski — Rule of Five in 2015 and Beyond: Target and Ligand Structural Limitations, Ligand Chemistry Structure and Drug Discovery Project Decisions

Advanced drug delivery reviews
2016 Mechanism / Preclinical Unspecified

2016 · Coplen — A revision in hydrogen isotopic composition of USGS42 and USGS43 human-hair stable isotopic reference materials for forensic science

Forensic science international
2016 Mechanism / Preclinical Unspecified

2016 · Zhao — Dock 'n roll: folding of a silk-inspired polypeptide into an amyloid-like beta solenoid

Soft matter
2016 Mechanism / Preclinical Unspecified

2016 · Ostojic — Is Melanin a Source of Bioactive Molecular Hydrogen?

Pharmacological research
2016 Mechanism / Preclinical Unspecified

2016 · Chetty — Multi-Drug Resistance Profile of PR20 HIV-1 Protease Is Attributed to Distorted Conformational and Drug Binding Landscape: Molecular Dynamics Insights

Journal of biomolecular structure & dynamics
2015 Mechanism / Preclinical Unspecified

2015 · Bhakat — Effect of T68A/N126Y mutations on the conformational and ligand binding landscape of Coxsackievirus B3 3C protease.

Molecular bioSystems
2015 Mechanism / Preclinical Unspecified

2015 · Bharty et al. — Synthesis, spectral characterization, thermal behaviour, antibacterial activity and DFT calculation on N'-[bis(methylsulfanyl)methylene]-2-hydroxybenzohydrazide and N'-(4-methoxybenzoyl)-hydrazinecarbodithioic acid ethyl ester.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
2015 Mechanism / Preclinical Unspecified

2015 · Oda et al. — Prediction of binding modes between protein L-isoaspartyl (D-aspartyl) O-methyltransferase and peptide substrates including isomerized aspartic acid residues using in silico analytic methods for the substrate screening.

Journal of pharmaceutical and biomedical analysis
2015 Mechanism / Preclinical Inhalation

2015 · Keles et al. — Can an innocent toy become dangerous? The hydrogen gas balloon burn.

Burns : journal of the International Society for Burn Injuries
2015 Mechanism / Preclinical Unspecified

2015 · Casanova et al. — Campylobacter concisus pseudo-outbreak caused by improved culture conditions.

Journal of clinical microbiology
2014 Mechanism / Preclinical InhalationBath / Topical

2014 · Chen — Controlling initial biodegradation of magnesium by a biocompatible strontium phosphate conversion coating

Acta biomaterialia
2012 Mechanism / Preclinical Unspecified

2012 · Wang et al. — Binding hot-spots in an antibody-ssDNA interface: a molecular dynamics study.

Molecular bioSystems
2012 Mechanism / Preclinical Unspecified

2012 · Hopper et al. — Evidence for the preservation of native inter- and intra-molecular hydrogen bonds in the desolvated FK-binding protein·FK506 complex produced by electrospray ionization.

Journal of the American Society for Mass Spectrometry
2011 Mechanism / Preclinical Unspecified

2011 · Schneider — The Trichomonas vaginalis Hydrogenosome Proteome Is Highly Reduced Relative to Mitochondria, Yet Complex Compared with Mitosomes

International journal for parasitology
2011 Mechanism / Preclinical InhalationBath / Topical

2011 · Gao — Fabrication and Characterization of Bioactive Composite Coatings on Mg-Zn-Ca Alloy by MAO/Sol-Gel

Journal of materials science. Materials in medicine
2011 Mechanism / Preclinical Unspecified

2011 · Liu — Quinazolines with Intra-Molecular Hydrogen Bonding Scaffold (iMHBS) as PI3K/mTOR Dual Inhibitors

Bioorganic & medicinal chemistry letters
2011 Mechanism / Preclinical Inhalation

2011 · Chai — Perfusion Electrodeposition of Calcium Phosphate on Additive Manufactured Titanium Scaffolds for Bone Engineering

Acta biomaterialia
2010 Mechanism / Preclinical InhalationDrinking (HRW)

2010 · Bolca — Microbial equol production attenuates colonic methanogenesis and sulphidogenesis in vitro.

Anaerobe
2008 Mechanism / Preclinical Inhalation

2008 · Kniess et al. — Practical experiences with the synthesis of [¹¹C]CH₃I through gas phase iodination using a TRACERlabFXC synthesis module

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
2005 Mechanism / Preclinical Inhalation

2005 · Decroos et al. — Isolation and characterisation of an equol-producing mixed microbial culture from a human faecal sample and its activity under gastrointestinal conditions

Archives of microbiology
2002 Mechanism / Preclinical Unspecified

2002 · Avvakumov et al. — Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol

The Journal of biological chemistry
2002 Mechanism / Preclinical InhalationDrinking (HRW)

2002 · Peterson — Tritium doses from chronic atmospheric releases: a new approach proposed for regulatory compliance.

Health physics
2000 Mechanism / Preclinical Drinking (HRW)

2000 · Pletnev — Crystal structure of bovine duodenase, a serine protease, with dual trypsin and chymotrypsin-like specificities.

Proteins
1999 Mechanism / Preclinical Unspecified

1999 · Nakayama — CTAB-mediated enrichment for active forms of novel dimeric maxizymes.

FEBS letters
1995 Mechanism / Preclinical Drinking (HRW)

1995 · Gillespie — Energetics of Molecular Hydrogen Oxidation in the Oral Pathogen Campylobacter rectus

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
1994 Mechanism / Preclinical Unspecified

1994 · Chakravarty — Drug–Protein Interactions: Refined Structures of Three Sulfonamide Drug Complexes of Human Carbonic Anhydrase I Enzyme

Journal of molecular biology
1992 Mechanism / Preclinical Unspecified

1992 · McGown — Regeneration of Functional Hemoglobin from Iron(III) Hemoglobin by Reduction with Hydrogen and a Heterogeneous Catalyst

Analytical biochemistry
1992 Mechanism / Preclinical Inhalation

1992 · Ellies — Crystallographic Changes in Calcium Phosphates During Plasma-Spraying

Biomaterials
1992 Mechanism / Preclinical Inhalation

1992 · Wong — A New Zinc Product for the Reduction of Water in Physiological Fluids to Hydrogen Gas for ²H/¹H Isotope Ratio Measurements

European journal of clinical nutrition
1991 Mechanism / Preclinical InhalationDrinking (HRW)

1991 · Kawano — Protective Effect of Rebamipide (OPC-12759) on the Gastric Mucosa in Rats and Humans

Nihon yakurigaku zasshi. Folia pharmacologica Japonica
1990 Mechanism / Preclinical Inhalation

1990 · Gibson — Alternative pathways for hydrogen disposal during fermentation in the human colon.

Gut
1986 Mechanism / Preclinical Inhalation

1986 · Sato — Hemodynamics of the gastric mucosa and gastric ulceration in rats and in patients with gastric ulcer.

Digestive diseases and sciences
1982 Mechanism / Preclinical Inhalation

1982 · Murakami — Contact electrode method in hydrogen gas clearance technique: a new method for determination of regional gastric mucosal blood flow in animals and humans.

Gastroenterology
1976 Mechanism / Preclinical Inhalation

1976 · Harding — Characterization of Bacteroides melaninogenicus.

Journal of clinical microbiology
1947 Mechanism / Preclinical Unspecified

1947 · FARKAS — On the activation of molecular hydrogen by Proteus vulgaris.

The Journal of biological chemistry